P353 The economics of 4 grams once daily mesalazine dosing compared with 4 grams twice daily in active ulcerative colitis
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چکیده
منابع مشابه
Cost and quality-adjusted life year differences in the treatment of active ulcerative colitis using once-daily 4 g or twice-daily 2g mesalazine dosing.
BACKGROUND Improved compliance in active ulcerative colitis (UC) is likely to improve healthcare efficiency by reducing time spent in active mild to moderate UC state. To establish whether once daily (OD) mesalazine offers economic advantages over twice daily (BD) dosing in active UC, we evaluated the outcomes and costs of a recently published randomized study. METHODS A cost-effectiveness mo...
متن کاملRandomised clinical trial: once- vs. twice-daily prolonged-release mesalazine for active ulcerative colitis.
BACKGROUND Aminosalicylates are first-choice treatment for mild-to-moderately active ulcerative colitis (UC); however, multi-dosing regimens are inconvenient. AIM To compare the efficacy and safety of once- (OD) vs. twice- (BD) daily prolonged-release mesalazine (Pentasa, Ferring, Saint-Prex, Switzerland) for active mild-to-moderate UC in a non-inferiority study. METHODS Eligible patients (...
متن کاملRandomised trial of once- or twice-daily MMX mesalazine for maintenance of remission in ulcerative colitis
AIM Maintenance treatment in ulcerative colitis should be as convenient as possible, to increase the chance of compliance. MMX mesalazine is a once-daily, high-strength (1.2 g/tablet) formulation of 5-aminosalicylic acid. This study evaluated the safety and efficacy of MMX mesalazine dosed once or twice daily as maintenance therapy in patients with ulcerative colitis. METHODS This multicentre...
متن کاملLong-term efficacy and safety of once-daily mesalazine granules for the treatment of active ulcerative colitis
In 1977, 5-aminosalicylic acid (5-ASA) was discovered as a therapeutically active moiety of sulfasalazine (SASP) and was launched for topical and oral therapy of ulcerative colitis (UC) in 1984. As a first-step, delivery systems had to be developed to protect 5-ASA against absorption in the upper gastrointestinal tract, resulting in different and competing strategies (azo compounds, controlled ...
متن کاملTreatment of streptococcal pharyngitis with once-daily compared with twice-daily amoxicillin: a noninferiority trial.
BACKGROUND Two relatively small previous studies comparing once-daily amoxicillin with conventional therapy for group A streptococcal (GAS) pharyngitis reported similar rates of bacteriologic success for each treatment group. The purpose of this study was to further evaluate once-daily amoxicillin for GAS pharyngitis in a larger study. METHODS In a single pediatric practice, from October thro...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2013
ISSN: 1873-9946
DOI: 10.1016/s1873-9946(13)60374-8